Nikki Glaser Calls Out Plastic Surgery, Ozempic Craze

Nikki Glaser kicked off the 2025 Golden Globes with a bang.

The comedian—who became the first ever solo female host of the awards show this year—took aim at the Ozempic craze in Hollywood with the first sentence of her opening monologue.

“Good evening, and welcome to the 82nd Golden Globes,” she greeted the star-studded crowd Jan. 5, “Ozempic’s biggest night!”

Later in the show, the comedian—who was also a nominee this year for her standup special Some Day You’ll Die—also joked about the celeb trend of getting plastic surgery but then attributing their changing looks to something else.

“I love where you put your cheekbones,” Nikki declared to laughs. “I, too, drink a lot of water. I don’t judge. I do it now, too.”

The 40-year-old added, “I love how meditating removes your eyelids, really convenient.”

Indeed, the FBoy Island host had previously revealed that she actually delayed her plans to potentially undergo invasive plastic surgery when she was invited to host the awards show. (Click here to see all the fashion on the red carpet.)